Iridocorneal endothelial (ICE) syndrome is a rare, irreversibly blinding ocular disorder with an unknown etiology. Lack of targeted effective drugs, inadequate disease prognosis, and high relapse rates post-surgery are the current challenges of ICE. Therefore, understanding its genomic and epigenomic landscape could aid in developing etiology-based therapies. This research, published in the Genes & Diseases journal by a team from Sun Yat-sen University, Guangzhou Medical University, Fujian Medical University, Shandong First Medical University, Huazhong University of Science and Technology, Nanchang University, Nanjing Medical University, China Three Gorges University, Hebei Medical University, Central South University, Xiamen University, Zhejiang University, and the...