Every year, approximately 8 million children worldwide are born with serious congenital conditions, many of which have a genetic origin.1,2 These genetic disorders are broadly classified into single-gene, multifactorial, and chromosomal disorders, reflecting the complexity of their origins. Image Credit: fizkes/Shutterstock.com Genetic conditions often result from inherited mutations passed down from one or both parents. In an inherited genetic disorder, a mutated gene is transmitted from a parent.3 However, not all genetic defects are inherited; some arise from new, spontaneous mutations (de-novo mutations) that occur independently of the parents' DNA.4 These can include chromosomal anomalies like Down syndrome or rare...