Nancy Guthrie led an active, vibrant life before her disappearance, taking part in social activities from book clubs and church to networking with other professionals like herself, according to her friends.Her disappearance shocked the world and those closest to her. People in her life are heartbroken by what is happening because of the way she lives her life, said Jacqueline Sharkey, Professor Emerita at the University of Arizona."She is completely devoted to her family, her faith, and her community," Sharkey said. "She's been deeply engaged in education issues, in issues of public health, such as saving the Poison Information Center….