Psychiatric disorders affect millions worldwide, but their diagnosis still relies on clinical observation instead of standard biological tests. In an attempt to identify reliable biomarkers, scientists in China have now launched the Brain-Gut Health Initiative, a large-scale longitudinal study combining neuroimaging, electrophysiology, microbiome sequencing, blood biomarkers, and clinical assessments across major psychiatric disorders. The findings revealed coordinated changes linking gut microbes, brain networks and symptoms—supporting the development of AI-assisted diagnosis and personalized therapies. Psychiatric disorders such as schizophrenia, depression, and bipolar disorder affect roughly one in seven people worldwide. While these disorders pose a major and growing global health challenge,…