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How flow chemistry transforms drug substance manufacture

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Sponsored Content by PharmaronReviewed by Maria OsipovaJun 19 2026Continuous flow manufacturing, also known as 'flow chemistry' or 'continuous flow', is a means of carrying out a chemical reaction using a continuous stream of different reagents contained within a pipe or tube and then mixed within a continuous device, such as a plug flow reactor (PFR) or continuous-stirred tank reactor (CSTR).1 Flow reactors have been used for continuous processing in the petrochemicals industry for decades, following the development of a large-scale Haber-Bosch process for ammonia production.2 These reactors have also been embedded within academia since the early 1990s. However, their adoption…

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